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BOTHELL, Wash., May 10, 2018 /PRNewswire/ — AGC Biologics, a all-around baton in analytic and bartering accomplishment of ameliorative proteins, appear today that in backward 2017 it entered into a bartering accumulation acceding with MacroGenics, a clinical-stage biopharmaceutical aggregation focused on advertent and developing avant-garde monoclonal antibody-based analysis for the analysis of cancer, for the accomplish of margetuximab, a clinical-stage, atypical immune-optimized monoclonal antibody.

AGC Biologics logo (PRNewsfoto/CMC Biologics)

AGC Biologics has provided absolute development and validation casework for margetuximab back 2014, and affairs to apparatus a alteration to bartering accumulation services.

Margetuximab is an investigational artefact that targets the animal epidermal beforehand agency receptor 2, or HER2. HER2 is bidding by bump beef in , gastroesophageal, float and added forms of solid bump cancers, authoritative it a key brand for biologic therapy. Margetuximab has an Fc domain, which was engineered to enhance assurance and activation of the allowed system.

“Patients with late-stage cancer, such as metastatic cancer, generally accept bound choices and greater ambiguity apropos what biologic will be best able as the aing footfall in their analysis path,” said Gustavo Mahler, Ph.D., President & Chief Executive Officer of AGC Biologics. “We’re captivated to assignment alongside MacroGenics in potentially bringing margetuximab to the bazaar — bushing a analytic need, and carrying a able new analysis option, if approved, with the adventitious to advisedly appulse patients’ lives.”

“We’re admiring to accept formed with AGC Biologics to accompany the development of margetuximab to this point, accepting MacroGenics afterpiece to our ambition of accouterment a possibly allusive beforehand to patients in need,” said Tom Spitznagel, Ph.D., Sr. Vice President, Biopharmaceutical Development & Accomplishment at MacroGenics. “AGC Biologics has been an important accomplice throughout the development and validation process, accouterment the expertise, technology and customized adaptability to facilitate the agitative aisle of margetuximab from development to pre-commercialization.”

About AGC Biologics AGC Biologics is a arch all-around Contract Development and Accomplishment Organization (CDMO), with a able charge to bear the accomplished accepted of account to our audience and partners. AGC Biologics is the artefact of the aggregation and affiliation of Asahi Glass Aggregation (AGC) Bioscience, Biomeva GmbH, and CMC Biologics. The aggregation currently employs added than 850 advisers worldwide. Our all-encompassing arrangement spans three continents, with cGMP-compliant accessories in Seattle, WA; Berkeley, CA; Copenhagen, Denmark; Heidelberg, Germany; Yokohama, Japan; and Chiba, Japan.

AGC Biologics offers abysmal industry ability and different customized casework for the scale-up and cGMP accomplish of protein-based therapeutics; from pre-clinical to bartering production, for beastly and microbial. Our chip account offerings accommodate corpuscle band development, bioprocess development, formulation, analytic testing, antibiotic biologic development and conjugation, corpuscle cyberbanking and storage, and protein announcement — including our proprietary CHEF1® Announcement Arrangement for beastly production. Further advice can be begin at www.agcbio.com

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